{"id":100352,"date":"2024-10-30T11:33:13","date_gmt":"2024-10-30T11:33:13","guid":{"rendered":"https:\/\/www.mymsd.ch\/it\/?page_id=100352"},"modified":"2026-02-17T09:17:08","modified_gmt":"2026-02-17T09:17:08","slug":"lyfnua","status":"publish","type":"page","link":"https:\/\/www.mymsd.ch\/it\/succinctstatement\/lyfnua\/","title":{"rendered":"Short Prescribing Information Lyfnua\u00ae (gefapixant)"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-object-object-font-size has-border-color has-has-red-border-color-border-color  mhh-mcn-v1-heading mhh-mcn-v1-heading--2fe7f4b0e03c337efee279d34d6e3d87\"><mark class=\"has-inline-color has-teal-500-color\">Informazione professionale breve di Lyfnua\u00ae (gefapixant)<\/mark><\/h1>\n\n\n\n<p class=\"has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--4c3f0e4cb99bfd819f920241ca1a8418\">\u25bc Questo medicamento \u00e8 soggetto a monitoraggio addizionale. Per ulteriori informazioni consultare l&#8217;informazione professionale (Lyfnua\u00ae) su <a href=\"https:\/\/www.swissmedicinfo-pro.ch\/ShowText.aspx?textType=FI&amp;lang=IT&amp;authNr=68065\">www.swissmedicinfo-pro.ch<\/a>.<\/p>\n\n\n\n<p class=\"has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--9a81bf86506aadcaebc140cfdd966b76\"><strong>Lyfnua\u00ae: PA: <\/strong>gefapixant. <strong>I:<\/strong> Adulti: indicato per il trattamento della tosse cronica refrattaria o della tosse cronica senza una causa spiegabile. <strong>P:<\/strong> Adulti: 45 mg bid con o senza cibo; In pazienti con disfunzione renale che non richiedono dialisi (eGFR &lt; 30 ml\/minuto\/1,73 m2) 45 mg una volta al giorno con o senza cibo. <strong>CI: <\/strong>Gravi reazioni di ipersensibilit\u00e0 a componenti. <strong>AP: <\/strong>Ipersensibilit\u00e0 ai sulfamidici; Apnea ostruttiva del sonno. <strong>IA:<\/strong> Solo un basso potenziale per clin. interazioni significative con inibitori o induttori del citocromo P450 (CYP) o degli enzimi glucuronosiltransferasi dell&#8217;acido uridina 5&#8242;-difosfoglucuronico (UGT). non clinico interazioni significative di\/con altri medicinali. <strong>G\/A:<\/strong> Non esaminato; non raccomandato. Contraccezione in pazienti in et\u00e0 fertile. <strong>EI:<\/strong> (molto comune): disgeusia (41%), ageusia (15%) e ipogeusia (11%). <strong>Conf: <\/strong>45 mg: 56 e 196 (2x 98) compresse rivestite con film.<strong> CD:<\/strong> B. <strong>TO:<\/strong> MSD Merck Sharp &amp; Dohme AG, Werftestrasse 4, 6005 Lucerna, Svizzera. (V1.0); CH-OGM-00001.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-gray-300-color has-alpha-channel-opacity has-gray-300-background-color has-background\" \/>\n\n\n\n<p class=\"has-object-object-font-size has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--b733f5b4f56db1b3655b95b994f478c4\"><em>Prima della prescrizione, consultare l\u2019informazione professionale completa, pubblicata sul sito web di Swissmedic (<a href=\"https:\/\/www.swissmedicinfo-pro.ch\/ShowText.aspx?textType=FI&amp;lang=IT&amp;authNr=68065\" target=\"_blank\" rel=\"noreferrer noopener\">www.swissmedicinfo-pro.ch<\/a>).<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Informazione professionale breve di Lyfnua\u00ae (gefapixant) \u25bc Questo medicamento \u00e8 soggetto a monitoraggio addizionale. Per ulteriori informazioni consultare l&#8217;informazione professionale [&hellip;]<\/p>\n","protected":false},"author":73172,"featured_media":0,"parent":99147,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mhh_sticky_footer_settings":{"entityId":0},"_mhh_sticky_footer_posts":"","_mhh_sticky_footer_expanded":false,"_mhh_mcn_text_direction":"","_mhh_mcn_language":"","_mhh_mcn_left_sidebar_settings":{"entityId":0},"_mhh_mcn_sidebar_settings":{"entityId":0},"mhh_mcn_side_navigation_style":{"fontSize":{"l":"","m":"","s":""},"lineHeight":{"l":1.5,"m":1.5,"s":1.5},"itemColor":"","hoverItemColor":"","currentItemColor":"","borderItemColor":"","backgroundItemHoverColor":"","themeColor":""},"_mhh_mcn_child_page_navigation":{"isActive":false,"isSticky":false},"hide_header":false,"show_top_bar":false,"hide_footer":false,"full_width_layout":false,"icon":null,"job_code":"","primary_tag":1129,"editor_notices":[],"mconnectHideShareThis":false,"footnotes":"","mconnectIsArchiveTemplate":false,"mconnectArchiveFiltersDisabled":false,"mconnectArchiveLockAllPresetFilters":false,"mconnectArchiveHidePageSubmenu":false,"mconnectArchiveShowParentPageOnly":false,"mconnectArchiveDefaultOrder":"DESC","mconnectArchiveDefaultOrderBy":"date","mconnectArchivePostsPerPage":12,"mconnectArchivePostTypes":[],"mconnectArchiveAllowFilterBy":["category","tx-content-type","tx-product","tx-pathology","tx-active-ingredient","tx-therapeutic-area"],"mconnectArchiveTaxonomyOrder":[],"mconnectArchiveFilterSorting":["active","is_keyword","is_date"],"mconnectArchiveContentItemStyle":{"showExcerpt":true,"showImage":true,"showIcon":false,"showPrimaryTag":true,"showBorder":false,"showDates":false,"showCta":true,"isCard":false,"hasBackground":false,"showMetadata":true},"mconnectArchiveLayout":{"type":"list","hasFeatured":false},"mconnectDynamicTaxonomyEntities":[],"mconnectArchiveTerms_category":[],"mconnectArchiveAllowTerms_category":[],"mconnectArchiveTerms_tx-content-type":[],"mconnectArchiveAllowTerms_tx-content-type":[],"mconnectArchiveTerms_tx-product":[],"mconnectArchiveAllowTerms_tx-product":[],"mconnectArchiveTerms_tx-pathology":[],"mconnectArchiveAllowTerms_tx-pathology":[],"mconnectArchiveTerms_tx-active-ingredient":[],"mconnectArchiveAllowTerms_tx-active-ingredient":[],"mconnectArchiveTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_dynamic-taxonomy":[],"mconnectArchiveLegacyDefaultTermsApplied":false,"mconnectContentUpdatesPerPage":10,"mconnectContentUpdatesViewMoreUrl":"","mconnectContentUpdatesTerms_tx-content-type":[],"mconnectContentUpdatesTerms_tx-product":[],"mconnectContentUpdatesTerms_tx-pathology":[],"mconnectContentUpdatesTerms_tx-active-ingredient":[],"mconnectContentUpdatesTerms_tx-therapeutic-area":[],"sidebar_toogle":0,"sidebar_toogle_notification_warning":true,"sidebar_toogle_notification_alert":true,"content_expiration_sidebar_date":"","content_expiration_sidebar_expired_post_status":"","content_expiration_sidebar_redirection":""},"categories":[1128],"tags":[1129],"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[501],"ga4_page_businessunit":[506],"ga4_page_campaign":[],"ga4_page_content_purpose":[1072],"ga4_page_customer_journey_stage":[],"ga4_page_customer_specialty":[],"ga4_page_experience":[],"ga4_page_indication":[],"ga4_page_material_intent":[713],"ga4_page_product":[817],"ga4_page_region":[946],"ga4_page_therapeuticarea":[1001],"tx-therapeutic-area":[284],"tx-product":[1257],"tx-pathology":[],"tx-content-type":[1130],"tx-active-ingredient":[],"access":[],"user_status":[],"user_role":[],"class_list":["post-100352","page","type-page","status-publish","hentry","category-kfi","tag-kfi"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Short Prescribing Information Lyfnua\u00ae (gefapixant) - MyMSD.ch IT<\/title>\n<meta name=\"robots\" content=\"noindex, nofollow\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Short Prescribing Information Lyfnua\u00ae (gefapixant) - MyMSD.ch IT\" \/>\n<meta property=\"og:description\" content=\"Informazione professionale breve di Lyfnua\u00ae (gefapixant) \u25bc Questo medicamento \u00e8 soggetto a monitoraggio addizionale. 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