{"id":94931,"date":"2025-08-22T06:39:26","date_gmt":"2025-08-22T06:39:26","guid":{"rendered":"https:\/\/www.mymsd.ch\/fr\/?post_type=product&p=94931"},"modified":"2025-08-22T06:40:02","modified_gmt":"2025-08-22T06:40:02","slug":"posologie","status":"publish","type":"product","link":"https:\/\/www.mymsd.ch\/fr\/products\/welireg\/posologie\/","title":{"rendered":"Posologie"},"content":{"rendered":"\n

Prise facile: une fois par jour1<\/sup><\/h2>\n\n\n\n

La dose recommand\u00e9e de WELIREG\u00ae est de 120 mg (trois comprim\u00e9s de 40 mg) une fois par jour jusqu\u2019\u00e0 la progression de la maladie ou l\u2019apparition d\u2019une toxicit\u00e9 inacceptable.1<\/sup><\/h3>\n\n\n\n
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Ne correspond pas \u00e0 la taille r\u00e9elle.<\/em>
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WELIREG\u00ae doit \u00eatre pris quotidiennement \u00e0 la m\u00eame heure pendant les repas ou en dehors .1<\/sup><\/strong><\/p>\n\n\n\n

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Ne pas \u00e9craser ou croquer les comprim\u00e9s, mais les avaler entiers.1<\/sup><\/strong><\/p>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n\n

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En cas d\u2019oubli d\u2019une dose de WELIREG\u00ae, on peut la prendre d\u00e8s que possible le jour m\u00eame.1<\/sup><\/strong><\/p>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n\n

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Si le patient ou la patiente vomit \u00e0 n\u2019importe quel moment apr\u00e8s la prise de WELIREG\u00ae, il ou elle ne doit pas prendre une autre dose, mais attendre le lendemain pour la prendre.<\/strong>1<\/strong><\/sup><\/p>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n\n

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Recommandations pour l\u2019ajustement de la posologie en cas d\u2019effets ind\u00e9sirables1<\/sup><\/h2>\n\n\n
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Adapt\u00e9 d\u2019apr\u00e8s l\u2019information professionnelle de WELIREG\u00ae (belzutifan).1<\/sup><\/em>
a. \u00c9valu\u00e9 selon l\u2019\u00e9chelle CTCAE (Common Terminology Criteria for Adverse Events [crit\u00e8res terminologiques g\u00e9n\u00e9raux des \u00e9v\u00e9nements ind\u00e9sirables]) du National Cancer Institute (NCI [institut national du cancer]) des \u00c9tats-Unis, version 5.0.1<\/sup><\/em><\/p>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n\n

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\n \n Des exemplaires des publications de l’\u00e9tude peuvent \u00eatre demand\u00e9s \u00e0 dpoc.switzerland@msd.com si n\u00e9cessaire.<\/span>\n <\/a><\/div>\n\n\n\n
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Abr\u00e9viations<\/strong>:<\/mark><\/em><\/h6>\n\n\n\n

Hb<\/strong>: h\u00e9moglobine; NCI CTCAE<\/strong>: crit\u00e8res terminologiques g\u00e9n\u00e9raux des \u00e9v\u00e9nements ind\u00e9sirables du National Cancer Institute (National Cancer Institute Common Terminology Criteria for Adverse Events); paO2<\/strong>: pression partielle en oxyg\u00e8ne.<\/em><\/p>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n

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R\u00e9f\u00e9rences:<\/strong> <\/mark><\/em><\/h6>\n\n\n\n
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  1. \n Information professionnelle de WELIREG\u00ae (Belzutifan),\u00a0www.swissmedicinfo.ch<\/a><\/mark><\/mark>, derni\u00e8re consultation le 22.08.2025.<\/em> <\/li>\n\n<\/ol>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n\n

    \u25bc Ce m\u00e9dicament fait l’objet d’une surveillance suppl\u00e9mentaire. Pour plus d\u2019informations, se r\u00e9f\u00e9rer \u00e0 l\u2019information professionnelle de WELIREG\u00ae disponible sous www.swissmedicinfo.ch<\/a>.<\/mark><\/em>

    Avant la prescription, veuillez consulter l\u2019information professionnelle compl\u00e8te publi\u00e9e sur     www.swissmedicinfo.ch<\/a>.<\/mark><\/em><\/p>\n\n\n

    \n \n Information professionnelle de WELIREG\u00ae<\/span>\n <\/a><\/div>\n\n\n
    \n \n Information professionnelle abr\u00e9g\u00e9e de WELIREG\u00ae<\/span>\n <\/a><\/div>\n","protected":false},"excerpt":{"rendered":"

    La dose recommand\u00e9e de WELIREG\u00ae est de 120\u00a0mg (trois comprim\u00e9s de 40\u00a0mg) une fois par jour jusqu\u2019\u00e0 la progression de la maladie ou l\u2019apparition d\u2019une toxicit\u00e9 inacceptable.<\/p>\n","protected":false},"author":202221,"featured_media":101007,"parent":99715,"menu_order":3,"template":"","meta":{"_mhh_sticky_footer_settings":{"entityId":0},"_mhh_sticky_footer_posts":"","_mhh_sticky_footer_expanded":false,"_mhh_mcn_text_direction":"","_mhh_mcn_language":"","_mhh_mcn_left_sidebar_settings":{"entityId":0},"_mhh_mcn_sidebar_settings":{"entityId":0},"mhh_mcn_side_navigation_style":{"fontSize":{"l":"","m":"","s":""},"lineHeight":{"l":1.5,"m":1.5,"s":1.5},"itemColor":"","hoverItemColor":"","currentItemColor":"","borderItemColor":"","backgroundItemHoverColor":"","themeColor":""},"_mhh_mcn_child_page_navigation":{"isActive":true,"isSticky":true},"hide_header":false,"show_top_bar":false,"hide_footer":false,"full_width_layout":false,"product_resource":[],"related_products":"","fact_sheet":null,"scientific_title":"","job_code":"","banner":101008,"primary_logo":null,"secondary_logo":null,"icon":null,"primary_tag":1524,"editor_notices":[],"mconnectHideShareThis":false,"footnotes":"","mconnectIsArchiveTemplate":false,"mconnectArchiveFiltersDisabled":false,"mconnectArchiveLockAllPresetFilters":false,"mconnectArchiveHidePageSubmenu":false,"mconnectArchiveShowParentPageOnly":false,"mconnectArchiveDefaultOrder":"DESC","mconnectArchiveDefaultOrderBy":"date","mconnectArchivePostsPerPage":12,"mconnectArchivePostTypes":[],"mconnectArchiveAllowFilterBy":["category","tx-content-type","tx-product","tx-pathology","tx-active-ingredient","tx-therapeutic-area"],"mconnectArchiveTaxonomyOrder":[],"mconnectArchiveFilterSorting":["active","is_keyword","is_date"],"mconnectArchiveContentItemStyle":{"showExcerpt":true,"showImage":true,"showIcon":false,"showPrimaryTag":true,"showBorder":false,"showDates":false,"showCta":true,"isCard":false,"hasBackground":false,"showMetadata":true},"mconnectArchiveLayout":{"type":"list","hasFeatured":false},"mconnectDynamicTaxonomyEntities":[],"mconnectArchiveTerms_category":[],"mconnectArchiveAllowTerms_category":[],"mconnectArchiveTerms_tx-content-type":[],"mconnectArchiveAllowTerms_tx-content-type":[],"mconnectArchiveTerms_tx-product":[],"mconnectArchiveAllowTerms_tx-product":[],"mconnectArchiveTerms_tx-pathology":[],"mconnectArchiveAllowTerms_tx-pathology":[],"mconnectArchiveTerms_tx-active-ingredient":[],"mconnectArchiveAllowTerms_tx-active-ingredient":[],"mconnectArchiveTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_dynamic-taxonomy":[],"mconnectArchiveLegacyDefaultTermsApplied":false,"mconnectContentUpdatesPerPage":10,"mconnectContentUpdatesViewMoreUrl":"","mconnectContentUpdatesTerms_tx-content-type":[],"mconnectContentUpdatesTerms_tx-product":[],"mconnectContentUpdatesTerms_tx-pathology":[],"mconnectContentUpdatesTerms_tx-active-ingredient":[],"mconnectContentUpdatesTerms_tx-therapeutic-area":[],"sidebar_toogle":0,"sidebar_toogle_notification_warning":true,"sidebar_toogle_notification_alert":true,"content_expiration_sidebar_date":"","content_expiration_sidebar_expired_post_status":"","content_expiration_sidebar_redirection":""},"categories":[],"tags":[1524],"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[957],"ga4_page_businessunit":[963],"ga4_page_campaign":[],"ga4_page_content_purpose":[992],"ga4_page_customer_journey_stage":[1012],"ga4_page_customer_specialty":[1052],"ga4_page_experience":[],"ga4_page_indication":[],"ga4_page_material_intent":[1206],"ga4_page_product":[1216],"ga4_page_region":[1462],"ga4_page_therapeuticarea":[1497],"tx-therapeutic-area":[627,931],"tx-product":[1522],"tx-pathology":[930,1525],"tx-content-type":[686,715],"tx-active-ingredient":[],"access":[],"user_status":[],"user_role":[],"class_list":["post-94931","product","type-product","status-publish","has-post-thumbnail","hentry","tag-welireg-2"],"yoast_head":"\nPosologie 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