{"id":100895,"date":"2025-08-22T06:47:27","date_gmt":"2025-08-22T06:47:27","guid":{"rendered":"https:\/\/www.mymsd.ch\/fr\/?post_type=product&p=100895"},"modified":"2025-08-22T06:47:29","modified_gmt":"2025-08-22T06:47:29","slug":"sequencage","status":"publish","type":"product","link":"https:\/\/www.mymsd.ch\/fr\/products\/welireg\/ls005\/sequencage\/","title":{"rendered":"S\u00e9quen\u00e7age"},"content":{"rendered":"\n

\u00c0 partir de quelle ligne de traitement WELIREG\u00ae peut-il \u00eatre utilis\u00e9 dans l\u2019aRCC?1<\/sup><\/h2>\n\n\n\n

WELIREG\u00ae en monoth\u00e9rapie est indiqu\u00e9 pour le traitement des patients adultes atteints de carcinome r\u00e9nal \u00e0 cellules claires (CCR) avanc\u00e9 non r\u00e9s\u00e9cable, qui a progress\u00e9 apr\u00e8s deux lignes de traitement ou plus, dont un inhibiteur du PD-(L)1 et un inhibiteur de tyrosine kinase VEGF.1<\/sup><\/strong><\/p>\n\n\n\n

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Ce graphique illustre l\u2019utilisation clinique la plus pr\u00e9coce possible de WELIREG\u00ae. Ces sc\u00e9narios ne repr\u00e9sentent pas toutes les options possibles pour la s\u00e9quence de traitement possible pour les patient(e)s atteint(e)s d\u2019un carcinome \u00e0 cellules r\u00e9nales avanc\u00e9.1<\/sup><\/mark><\/p>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n\n

<\/div>\n\n\n\n
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\n \n Des exemplaires des publications de l’\u00e9tude peuvent \u00eatre demand\u00e9s \u00e0 dpoc.switzerland@msd.com si n\u00e9cessaire.<\/span>\n <\/a><\/div>\n\n\n
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Abr\u00e9viations<\/strong><\/em><\/strong><\/em><\/strong><\/em>:<\/h6>\n\n\n\n

1\/2\/3\/4L<\/strong>: premi\u00e8re\/deuxi\u00e8me\/troisi\u00e8me\/quatri\u00e8me ligne; aRCC<\/strong>: carcinome \u00e0 cellules r\u00e9nales avanc\u00e9 (advanced renal cell carcinoma); CTLA-4<\/strong>: antig\u00e8ne 4 du lymphocyte T cytotoxique (cytotoxic T-lymphocyte antigen 4); PD-1<\/strong>: prot\u00e9ine 1 de la mort cellulaire programm\u00e9e (programmed cell death protein 1); PD-L1<\/strong>: ligand 1 de mort cellulaire programm\u00e9e (Programmed death-ligand 1); TKI<\/strong>: inhibiteur de la tyrosine kinase (tyrosine kinase inhibitor); VEGF\/R<\/strong>: facteur\/r\u00e9cepteur du facteur de croissance de l’endoth\u00e9lium vasculaire (vascular endothelial growth factor\/receptor).<\/em><\/p>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n

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R\u00e9f\u00e9rences<\/em><\/em>:<\/strong><\/h6>\n\n\n\n
    \n \n
  1. \n Information professionnelle de WELIREG\u00ae (belzutifan),\u00a0www.swissmedicinfo.ch<\/a><\/mark><\/mark>, derni\u00e8re consultation le 22.08.2025.<\/em> <\/li>\n\n<\/ol>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n\n

    \u25bc Ce m\u00e9dicament fait l’objet d’une surveillance suppl\u00e9mentaire. Pour plus d\u2019informations, se r\u00e9f\u00e9rer \u00e0 l\u2019information professionnelle de WELIREG\u00ae disponible sous www.swissmedicinfo.ch<\/a>.<\/mark><\/em>

    Avant la prescription, veuillez consulter l\u2019information professionnelle compl\u00e8te publi\u00e9e sur     www.swissmedicinfo.ch<\/a>.<\/mark><\/em><\/p>\n\n\n

    \n \n Information professionnelle de WELIREG\u00ae<\/span>\n <\/a><\/div>\n\n\n
    \n \n Information professionnelle abr\u00e9g\u00e9e de WELIREG\u00ae<\/span>\n <\/a><\/div>\n","protected":false},"excerpt":{"rendered":"

    \u00c0 partir de quelle ligne de traitement WELIREG\u00ae peut-il \u00eatre utilis\u00e9 dans l\u2019aRCC?<\/p>\n","protected":false},"author":202221,"featured_media":100968,"parent":100887,"menu_order":8,"template":"","meta":{"_mhh_sticky_footer_settings":{"entityId":0},"_mhh_sticky_footer_posts":"","_mhh_sticky_footer_expanded":false,"_mhh_mcn_text_direction":"","_mhh_mcn_language":"","_mhh_mcn_left_sidebar_settings":{"entityId":0},"_mhh_mcn_sidebar_settings":{"entityId":0},"mhh_mcn_side_navigation_style":{"fontSize":{"l":"","m":"","s":""},"lineHeight":{"l":1.5,"m":1.5,"s":1.5},"itemColor":"","hoverItemColor":"","currentItemColor":"","borderItemColor":"","backgroundItemHoverColor":"","themeColor":""},"_mhh_mcn_child_page_navigation":{"isActive":true,"isSticky":true},"hide_header":false,"show_top_bar":false,"hide_footer":false,"full_width_layout":false,"product_resource":[],"related_products":"","fact_sheet":null,"scientific_title":"","job_code":"","banner":100969,"primary_logo":null,"secondary_logo":null,"icon":null,"primary_tag":1524,"editor_notices":[],"mconnectHideShareThis":false,"footnotes":"","mconnectIsArchiveTemplate":false,"mconnectArchiveFiltersDisabled":false,"mconnectArchiveLockAllPresetFilters":false,"mconnectArchiveHidePageSubmenu":false,"mconnectArchiveShowParentPageOnly":false,"mconnectArchiveDefaultOrder":"DESC","mconnectArchiveDefaultOrderBy":"date","mconnectArchivePostsPerPage":12,"mconnectArchivePostTypes":[],"mconnectArchiveAllowFilterBy":["category","tx-content-type","tx-product","tx-pathology","tx-active-ingredient","tx-therapeutic-area"],"mconnectArchiveTaxonomyOrder":[],"mconnectArchiveFilterSorting":["active","is_keyword","is_date"],"mconnectArchiveContentItemStyle":{"showExcerpt":true,"showImage":true,"showIcon":false,"showPrimaryTag":true,"showBorder":false,"showDates":false,"showCta":true,"isCard":false,"hasBackground":false,"showMetadata":true},"mconnectArchiveLayout":{"type":"list","hasFeatured":false},"mconnectDynamicTaxonomyEntities":[],"mconnectArchiveTerms_category":[],"mconnectArchiveAllowTerms_category":[],"mconnectArchiveTerms_tx-content-type":[],"mconnectArchiveAllowTerms_tx-content-type":[],"mconnectArchiveTerms_tx-product":[],"mconnectArchiveAllowTerms_tx-product":[],"mconnectArchiveTerms_tx-pathology":[],"mconnectArchiveAllowTerms_tx-pathology":[],"mconnectArchiveTerms_tx-active-ingredient":[],"mconnectArchiveAllowTerms_tx-active-ingredient":[],"mconnectArchiveTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_dynamic-taxonomy":[],"mconnectArchiveLegacyDefaultTermsApplied":false,"mconnectContentUpdatesPerPage":10,"mconnectContentUpdatesViewMoreUrl":"","mconnectContentUpdatesTerms_tx-content-type":[],"mconnectContentUpdatesTerms_tx-product":[],"mconnectContentUpdatesTerms_tx-pathology":[],"mconnectContentUpdatesTerms_tx-active-ingredient":[],"mconnectContentUpdatesTerms_tx-therapeutic-area":[],"sidebar_toogle":0,"sidebar_toogle_notification_warning":true,"sidebar_toogle_notification_alert":true,"content_expiration_sidebar_date":"","content_expiration_sidebar_expired_post_status":"","content_expiration_sidebar_redirection":""},"categories":[693,791],"tags":[1524,1523],"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[957],"ga4_page_businessunit":[963],"ga4_page_campaign":[],"ga4_page_content_purpose":[],"ga4_page_customer_journey_stage":[],"ga4_page_customer_specialty":[],"ga4_page_experience":[],"ga4_page_indication":[],"ga4_page_material_intent":[1206],"ga4_page_product":[],"ga4_page_region":[],"ga4_page_therapeuticarea":[],"tx-therapeutic-area":[627,931],"tx-product":[1522],"tx-pathology":[930],"tx-content-type":[686],"tx-active-ingredient":[],"access":[],"user_status":[],"user_role":[],"class_list":["post-100895","product","type-product","status-publish","has-post-thumbnail","hentry","category-indications","category-oncology","tag-welireg-2","tag-welireg"],"yoast_head":"\nS\u00e9quen\u00e7age 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