{"id":93399,"date":"2023-10-16T13:49:58","date_gmt":"2023-10-16T13:49:58","guid":{"rendered":"https:\/\/www.mymsd.ch\/fr\/?p=93399"},"modified":"2025-11-07T18:48:24","modified_gmt":"2025-11-07T18:48:24","slug":"motzer-et-al-publication-ae-management-arcc","status":"publish","type":"post","link":"https:\/\/www.mymsd.ch\/fr\/oncology\/onco-news\/motzer-et-al-publication-ae-management-arcc\/","title":{"rendered":"R\u00e9actions ind\u00e9sirables chez vos patients atteints du RCC avanc\u00e9 : comment les g\u00e9rer?"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/www.mymsd.ch\/de\/wp-content\/uploads\/sites\/13\/2023\/10\/Spot_COVID-19-no-masks-white_lo_96dpi.jpg?w=1024\" alt=\"R\u00e9actions ind\u00e9sirables chez vos patients atteints du RCC avanc\u00e9 : comment les g\u00e9rer? banner\" class=\"wp-image-107687\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading has-border-color has-has-red-border-color-border-color  mhh-mcn-v1-heading mhh-mcn-v1-heading--e6c712aae5fedf298f3b04d250ffb7fe\">Voici comment g\u00e9rer les r\u00e9actions ind\u00e9sirables chez vos patients atteints de RCC avanc\u00e9 sous traitement par PEM+LEN.<\/h3>\n\n\n\n<p class=\"has-positive-1-font-size has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--a0739d4cbc2e11764f7bdd1935c67bbd\">Jetez un coup d&rsquo;\u0153il \u00e0 la publication de Motzer et al. et d\u00e9couvrez tout sur la caract\u00e9risation et la gestion des r\u00e9actions ind\u00e9sirables dans l&rsquo;\u00e9tude CLEAR chez les patients atteints de RCC avanc\u00e9 sous traitement par PEM+LEN.<\/p>\n\n\n<div class=\"mhh-mcn-v1-links mhh-mcn-v1-links--26b2619c839a0211796a50bc53d1e591\">\n    <a class=\"mhh-mcn-v1-link mhh-mcn-v1-link--8658ae67a48b9f112f93ae73479eca98 mhh-mcn-v1-link--is-variation mhh-mcn-v1-link--button-primary\" href=\"https:\/\/www.mymsd.ch\/de\/wp-content\/uploads\/sites\/13\/2023\/10\/Motzer-AE-Management-2023.pdf\" target=\"_self\" aria-label=\"Motzer-AE-Management-2023 pdf link\">\n                    <span class=\"mhh-mcn-v1-link__label\">Vers la publication<\/span>\n                <\/a><\/div>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\r\n<div class=\"inpsyde-iframe is-responsive has-transparent-background-color\">\r\n    <iframe loading=\"lazy\" height=\"400\" referrerpolicy=\"no-referrer-when-downgrade\" title=\"Ce contenu vous a-t-il \u00e9t\u00e9 pertinent ?\" src=\"https:\/\/go.screver.com\/msd-ch-cx\/newsroom-articles?lang=fr&amp;hideHeader=true\" width=\"100%\"><\/iframe>\r\n<\/div>\n\n\n<section class=\"mhh-mcn-v1-section mhh-mcn-v1-section--fce9440301bbb24e833b0be682dfe8b9 mhh-mcn-section mhh-mcn-v1-section--align-full\">\n    <div class=\"mhh-mcn-container\">\n    \n\n<h3 class=\"wp-block-heading has-border-color 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with-aspect-ratio--content-grid\">\n    <div class=\"figure-outer\">\n    <div class=\"figure-inner\">\n                            <img loading=\"lazy\" decoding=\"async\"\n        class=\"mhh-mcn-image mhh-mcn-image--2048x2048 wp-image-102293\"\n        src=\"https:\/\/www.mymsd.ch\/fr\/wp-content\/uploads\/sites\/30\/2025\/11\/Teaser-ESMO-2025.jpg?w=1536&#038;quality=80&#038;lossy=1\"\n        width=\"1536\"\n        height=\"1149\"\n                alt=\"Image: ESMO 2025\"\n            \/>\n                <\/div>\n    <\/div>\n    <\/figure>\n<\/div>\n\n<article class=\"mhh-mcn-v1-content-item-content\">\n    <section class=\"mhh-mcn-v1-content-item-content-body\">\n        \n<span class=\"mhh-mcn-v1-content-item-primary-tag mhh-mcn-v1-content-item-primary-tag--c06ec76831703497d2b89abb588910eb\" title=\"This item has been tagged as: Congress Update\">\n    Congress Update<\/span>\n        <header class=\"mhh-mcn-v1-content-item-header\">\n    \n    <span 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mhh-mcn-v1-content-item-excerpt--c06ec76831703497d2b89abb588910eb\">\n    De nombreuses avanc\u00e9es importantes dans la recherche sur le cancer ont \u00e9t\u00e9 pr\u00e9sent\u00e9es lors du congr\u00e8s ESMO 2025. Nous avons r\u00e9sum\u00e9 pour vous les donn\u00e9es de suivi de nos \u00e9tudes KEYNOTE.<\/p>\n        \n<div class=\"mhh-mcn-v1-content-item-meta mhh-mcn-badge-container\">\n    \n    \n    <\/div>\n    <\/section>\n    <div class=\"mhh-mcn-v1-content-item-footer\">\n    \n    \n    <\/div>\n<\/article>\n<\/div>\n<div\n    class=\"mhh-mcn-column mhh-mcn-column--12 mhh-mcn-column--m-6 mhh-mcn-column--l-4 mhh-mcn-v1-content-item mhh-mcn-v1-content-item--956169d9a66758ddc461536c752ac404 mhh-mcn-v1-content-item--type-post mhh-mcn-v1-content-item--display-media-style mhh-mcn-v1-content-item--has-featured-image\">\n    <div class=\"mhh-mcn-v1-content-item-featured-image\">\n    <figure class=\"mhh-mcn-v1-image mhh-mcn-v1-image--213c6fc0032e1b919f706ca7d2d0d6e1 with-aspect-ratio with-aspect-ratio--content-grid\">\n    <div class=\"figure-outer\">\n    <div class=\"figure-inner\">\n                            <img decoding=\"async\"\n        class=\"mhh-mcn-image mhh-mcn-image--2048x2048 wp-image-101564\"\n        src=\"https:\/\/www.mymsd.ch\/fr\/wp-content\/uploads\/sites\/30\/2025\/10\/F-KN689-ONR-Teaser.jpg?w=1536&#038;quality=80&#038;lossy=1\"\n        width=\"1536\"\n        height=\"1149\"\n        loading=\"lazy\"        alt=\"\"\n            \/>\n                <\/div>\n    <\/div>\n    <\/figure>\n<\/div>\n\n<article class=\"mhh-mcn-v1-content-item-content\">\n    <section class=\"mhh-mcn-v1-content-item-content-body\">\n        \n<span class=\"mhh-mcn-v1-content-item-primary-tag mhh-mcn-v1-content-item-primary-tag--c06ec76831703497d2b89abb588910eb\" title=\"This item has been tagged as: CETEC\">\n    CETEC<\/span>\n        <header class=\"mhh-mcn-v1-content-item-header\">\n    \n    <span class=\"mhh-mcn-v1-content-item-icon-type mhh-mcn-v1-content-item-icon-type--post\">\n    <span class=\"mhh-mcn-v1-content-item-icon-type__icon\">\n    \n<svg width=\"1em\" height=\"1em\" class=\"mh-icon mh-icon--kind-generic mh-icon--name-arrow-right mh-icon--arrow-right\" role=\"img\" aria-hidden=\"true\">\n    \n    \n    <use xlink:href=\"https:\/\/www.mymsd.ch\/fr\/wp-content\/themes\/cex-wpvip-mhh-mconnect-theme-new-3.0\/modules\/icons\/resources\/icons\/svg\/generic\/arrow-right.svg#arrow-right\"><\/use>\n<\/svg>\n    <\/span>\n    <\/span>\n    <h2 class=\"mhh-mcn-v1-content-item-title mhh-mcn-v1-content-item-title--c06ec76831703497d2b89abb588910eb\">\n    \n    <a class=\"mhh-mcn-v1-content-item-title__link\" href=\"https:\/\/www.mymsd.ch\/fr\/oncology\/onco-news\/keytruda-comme-option-de-traitement-perioperatoire-dans-le-cetec\/\" target=\"_self\">\n        KEYTRUDA\u00ae NOUVELLEMENT approuv\u00e9 comme option de traitement p\u00e9riop\u00e9ratoire pour le CETEC avec un CPS \u2265 1    <\/a>\n    <\/h2>\n\n    <\/header>\n\n        <p class=\"mhh-mcn-v1-content-item-excerpt mhh-mcn-v1-content-item-excerpt--c06ec76831703497d2b89abb588910eb\">\n    Swissmedic a autoris\u00e9 KEYTRUDA\u00ae dans une nouvelle indication pour le traitement du CETEC.<\/p>\n        \n<div class=\"mhh-mcn-v1-content-item-meta mhh-mcn-badge-container\">\n    \n    \n    <\/div>\n    <\/section>\n    <div class=\"mhh-mcn-v1-content-item-footer\">\n    \n    \n    <\/div>\n<\/article>\n<\/div>\n<div\n    class=\"mhh-mcn-column mhh-mcn-column--12 mhh-mcn-column--m-6 mhh-mcn-column--l-4 mhh-mcn-v1-content-item mhh-mcn-v1-content-item--c3a7ac3db8fe6f78299b6bd7af358e46 mhh-mcn-v1-content-item--type-post mhh-mcn-v1-content-item--display-media-style mhh-mcn-v1-content-item--has-featured-image\">\n    <div class=\"mhh-mcn-v1-content-item-featured-image\">\n    <figure class=\"mhh-mcn-v1-image mhh-mcn-v1-image--a673370a25021fe1fba277e2a1d91f63 with-aspect-ratio with-aspect-ratio--content-grid\">\n    <div class=\"figure-outer\">\n    <div class=\"figure-inner\">\n                            <img decoding=\"async\"\n        class=\"mhh-mcn-image mhh-mcn-image--2048x2048 wp-image-100550\"\n        src=\"https:\/\/www.mymsd.ch\/fr\/wp-content\/uploads\/sites\/30\/2025\/06\/F-KN868-ONR-Teaser.jpg?w=1536&#038;quality=80&#038;lossy=1\"\n        width=\"1536\"\n        height=\"1149\"\n        loading=\"lazy\"        alt=\"\"\n            \/>\n                <\/div>\n    <\/div>\n    <\/figure>\n<\/div>\n\n<article class=\"mhh-mcn-v1-content-item-content\">\n    <section class=\"mhh-mcn-v1-content-item-content-body\">\n        \n<span class=\"mhh-mcn-v1-content-item-primary-tag mhh-mcn-v1-content-item-primary-tag--c06ec76831703497d2b89abb588910eb\" title=\"This item has been tagged as: Cancer de l&#039;endom\u00e8tre\">\n    Cancer de l&rsquo;endom\u00e8tre<\/span>\n        <header class=\"mhh-mcn-v1-content-item-header\">\n    \n    <span class=\"mhh-mcn-v1-content-item-icon-type mhh-mcn-v1-content-item-icon-type--post\">\n    <span class=\"mhh-mcn-v1-content-item-icon-type__icon\">\n    \n<svg width=\"1em\" height=\"1em\" class=\"mh-icon mh-icon--kind-generic mh-icon--name-arrow-right mh-icon--arrow-right\" role=\"img\" aria-hidden=\"true\">\n    \n    \n    <use xlink:href=\"https:\/\/www.mymsd.ch\/fr\/wp-content\/themes\/cex-wpvip-mhh-mconnect-theme-new-3.0\/modules\/icons\/resources\/icons\/svg\/generic\/arrow-right.svg#arrow-right\"><\/use>\n<\/svg>\n    <\/span>\n    <\/span>\n    <h2 class=\"mhh-mcn-v1-content-item-title mhh-mcn-v1-content-item-title--c06ec76831703497d2b89abb588910eb\">\n    \n    <a class=\"mhh-mcn-v1-content-item-title__link\" href=\"https:\/\/www.mymsd.ch\/fr\/oncology\/onco-news\/keytruda-nouvellement-approuve-pour-le-cancer-de-lendometre-avec-dmmr\/\" target=\"_self\">\n        KEYTRUDA\u00ae NOUVELLEMENT approuv\u00e9 pour le cancer de l\u2019endom\u00e8tre avec dMMR    <\/a>\n    <\/h2>\n\n    <\/header>\n\n        <p class=\"mhh-mcn-v1-content-item-excerpt mhh-mcn-v1-content-item-excerpt--c06ec76831703497d2b89abb588910eb\">\n    Swissmedic a autoris\u00e9 KEYTRUDA\u00ae dans une nouvelle indication pour le traitement du cancer de l&rsquo;endom\u00e8tre.<\/p>\n        \n<div class=\"mhh-mcn-v1-content-item-meta mhh-mcn-badge-container\">\n    \n    \n    <\/div>\n    <\/section>\n    <div class=\"mhh-mcn-v1-content-item-footer\">\n    \n    \n    <\/div>\n<\/article>\n<\/div>\n    <\/div>\n\n    <\/div>\n\n    <\/div>\n<\/section>\n\n\n\n<h5 class=\"wp-block-heading has-border-color has-has-red-border-color-border-color  mhh-mcn-v1-heading mhh-mcn-v1-heading--2b718b08e5528de44ac65368647d65ed\"><strong>Referenzen<span class=\"has-inline-color has-grey-color\">:<\/span><\/strong><\/h5>\n\n\n\n<ol class=\"mhh-mcn-v2-clist mhh-mcn-v2-clist--f563246f153deae43ded190df335f0e6 mhh-mcn-list mhh-mcn-v2-clist--ordered mhh-mcn-v2-clist--ordered-decimal\" dir=\"ltr\" lang=\"fr-FR\" start=\"1\">\n    \n<li class=\"mhh-mcn-list-item mhh-mcn-v2-list-item\">\n    Fachinformation KEYTRUDA\u00ae (Pembrolizumab), www.swissmedicinfo.ch.    <\/li>\n\n\n<li class=\"mhh-mcn-list-item mhh-mcn-v2-list-item\">\n    Fachinformation KISPLYX\u00ae (Lenvatinib), www.swissmedicinfo.ch.    <\/li>\n\n\n<li class=\"mhh-mcn-list-item mhh-mcn-v2-list-item\">\n    Motzer R, George S, Merchan JR, et al. Characterization and management of adverse reactions from the CLEAR study in advanced renal cell carcinoma treated with lenvatinib plus pembrolizumab. The Oncologist. 2023;28(6):501-509. doi.org\/10.1093\/oncolo\/oyac269    <\/li>\n\n<\/ol>\n\n\n\n    <a class=\"mhh-mcn-v1-link mhh-mcn-v1-link--e8303c65a6b0b1dd0f6ff8f482481a09 mhh-mcn-v1-link--is-variation mhh-mcn-v1-link--button-primary\" href=\"https:\/\/swissmedicinfo.ch\/showText.aspx?textType=FI&#038;lang=FR&#038;authNr=66231&#038;supportMultipleResults=1\" target=\"_blank\" rel=\"noopener noreferrer\">\n                    <span class=\"mhh-mcn-v1-link__label\">Information professionnelle de KEYTRUDA\u00ae<\/span>\n                <\/a>\n\n\n<div class=\"mhh-mcn-v1-links mhh-mcn-v1-links--9aea451e9ffb8760f8a8d77ab7513c54\">\n    <a class=\"mhh-mcn-v1-link mhh-mcn-v1-link--f4064f2a8c66387db181153640dbdd02 mhh-mcn-v1-link--is-variation mhh-mcn-v1-link--button-primary\" href=\"https:\/\/www.swissmedicinfo-pro.ch\/showText.aspx?textType=FI&#038;lang=fr&#038;authNr=66085&#038;supportMultipleResults=1\" target=\"_blank\" rel=\"noopener noreferrer\" aria-label=\"Information professionnelle de KISPLYX\u00ae\">\n                    <span class=\"mhh-mcn-v1-link__label\">Information professionnelle de KISPLYX\u00ae<\/span>\n                <\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Voici comment g\u00e9rer les r\u00e9actions ind\u00e9sirables chez vos patients atteints de RCC avanc\u00e9 sous traitement par PEM+LEN. Jetez un coup [&hellip;]<\/p>\n","protected":false},"author":384,"featured_media":93400,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_mhh_sticky_footer_settings":{"entityId":0},"_mhh_sticky_footer_posts":"","_mhh_sticky_footer_expanded":false,"_mhh_mcn_text_direction":"","_mhh_mcn_language":"","_mhh_mcn_left_sidebar_settings":{"entityId":0},"_mhh_mcn_sidebar_settings":{"entityId":0},"mhh_mcn_side_navigation_style":{"fontSize":{"l":"","m":"","s":""},"lineHeight":{"l":1.5,"m":1.5,"s":1.5},"itemColor":"","hoverItemColor":"","currentItemColor":"","borderItemColor":"","backgroundItemHoverColor":"","themeColor":""},"_mhh_mcn_child_page_navigation":{"isActive":false,"isSticky":false},"hide_header":false,"show_top_bar":false,"hide_footer":false,"full_width_layout":false,"icon":null,"job_code":"","hide_featured_image":true,"primary_tag":598,"editor_notices":[],"mconnectHideShareThis":false,"footnotes":"","sidebar_toogle":0,"sidebar_toogle_notification_warning":true,"sidebar_toogle_notification_alert":true,"content_expiration_sidebar_date":"","content_expiration_sidebar_expired_post_status":"","content_expiration_sidebar_redirection":""},"categories":[792,791,1],"tags":[598],"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[957],"ga4_page_businessunit":[963],"ga4_page_campaign":[],"ga4_page_content_purpose":[],"ga4_page_customer_journey_stage":[],"ga4_page_customer_specialty":[],"ga4_page_experience":[],"ga4_page_indication":[],"ga4_page_material_intent":[1206],"ga4_page_product":[],"ga4_page_region":[],"ga4_page_therapeuticarea":[],"tx-therapeutic-area":[627],"tx-product":[],"tx-pathology":[],"tx-content-type":[],"tx-active-ingredient":[],"access":[],"user_status":[],"user_role":[],"class_list":["post-93399","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-onco-news","category-oncology","category-uncategorized","tag-keytruda"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>R\u00e9actions ind\u00e9sirables chez vos patients atteints du RCC avanc\u00e9 : comment les g\u00e9rer? - MyMSD.ch FR Onco News<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.mymsd.ch\/fr\/oncology\/onco-news\/motzer-et-al-publication-ae-management-arcc\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"R\u00e9actions ind\u00e9sirables chez vos patients atteints du RCC avanc\u00e9 : comment les g\u00e9rer? - MyMSD.ch FR Onco News\" \/>\n<meta property=\"og:description\" content=\"Voici comment g\u00e9rer les r\u00e9actions ind\u00e9sirables chez vos patients atteints de RCC avanc\u00e9 sous traitement par PEM+LEN. 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