{"id":97799,"date":"2024-10-30T11:33:04","date_gmt":"2024-10-30T11:33:04","guid":{"rendered":"https:\/\/www.mymsd.ch\/fr\/?page_id=97799"},"modified":"2026-02-17T09:19:28","modified_gmt":"2026-02-17T09:19:28","slug":"lyfnua","status":"publish","type":"page","link":"https:\/\/www.mymsd.ch\/fr\/succinctstatement\/lyfnua\/","title":{"rendered":"Information professionnelle abr\u00e9g\u00e9e de Lyfnua\u00ae (gefapixant)"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-object-object-font-size has-border-color has-has-red-border-color-border-color  mhh-mcn-v1-heading mhh-mcn-v1-heading--1f7c5f6abd4fe0c117bb2913cf2ad1a0\"><mark class=\"has-inline-color has-teal-500-color\">Information professionnelle abr\u00e9g\u00e9e de Lyfnua\u00ae (gefapixant)<\/mark><\/h1>\n\n\n\n<p class=\"has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--254c11eb401b1df4924e8e2f0ccafd3b\">\u25bc Ce m\u00e9dicament fait l\u2019objet d\u2019une surveillance suppl\u00e9mentaire. Pour plus d\u2019informations, se r\u00e9f\u00e9rer \u00e0 l&rsquo;information professionnelle (Lyfnua\u00ae) disponible sous <a href=\"https:\/\/www.swissmedicinfo-pro.ch\/ShowText.aspx?textType=FI&amp;lang=FR&amp;authNr=68065\">www.swissmedicinfo-pro.ch<\/a>.<\/p>\n\n\n\n<p class=\"has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--bd426fa5ce30eb493a77eb955a5ba775\"><strong>Lyfnua\u00ae: C: <\/strong>gefapixant. <strong>I:<\/strong> Adultes: indiqu\u00e9 pour le traitement de la toux chronique r\u00e9fractaire ou de la toux chronique inexpliqu\u00e9e. <strong>Po:<\/strong> Adultes: 45 mg bid avec ou sans nourriture; Chez les patients insuffisants r\u00e9naux ne n\u00e9cessitant pas de dialyse (DFGe &lt; 30 ml\/minute\/1,73 m2) 45 mg une fois par jour avec ou sans nourriture. <strong>CI: <\/strong>R\u00e9action d&rsquo;hypersensibilit\u00e9 s\u00e9v\u00e8re aux composants. <strong>Pr:<\/strong> Hypersensibilit\u00e9 aux sulfamides; Apn\u00e9e obstructive du sommeil.<strong> IA: <\/strong>seulement un faible potentiel pour les interactions clin. significatives avec des inhibiteurs ou des inducteurs du cytochrome P450 (CYP) ou des enzymes uridine 5&prime;-diphosphoglucuronique acide glucuronosyltransf\u00e9rase (UGT). Pas d\u2019interactions cliniques significatives sur Lyfnua\/sur d&rsquo;autres m\u00e9dicaments. <strong>G\/A: <\/strong>Non examin\u00e9; non recommand\u00e9. Contraception chez les patientes en \u00e2ge de procr\u00e9er.<strong> EI:<\/strong> (tr\u00e8s fr\u00e9quents): dysgueusie (41%), agueusie (15%) hypogueusie (11%). <strong>P:<\/strong> 45 mg: 56 et 196 (2 x 98) comprim\u00e9s pellicul\u00e9s. <strong>CR:<\/strong> B. <strong>Td\u2019a: <\/strong>MSD Merck Sharp &amp; Dohme AG, Werftestrasse 4, 6005 Lucerne, Suisse. (V1.0); CH-OGM-00001.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-gray-300-color has-alpha-channel-opacity has-gray-300-background-color has-background\" \/>\n\n\n\n<p class=\"has-object-object-font-size has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--610ac78085dddc734bda4da6feed748f\"><em>Avant de prescrire, veuillez consulter l\u2019information professionnelle compl\u00e8te publi\u00e9e sur la page d&rsquo;accueil de Swissmedic (<a href=\"https:\/\/www.swissmedicinfo-pro.ch\/ShowText.aspx?textType=FI&amp;lang=FR&amp;authNr=68065\" target=\"_blank\" rel=\"noreferrer noopener\">www.swissmedicinfo-pro.ch<\/a>).<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Information professionnelle abr\u00e9g\u00e9e de Lyfnua\u00ae (gefapixant) \u25bc Ce m\u00e9dicament fait l\u2019objet d\u2019une surveillance suppl\u00e9mentaire. Pour plus d\u2019informations, se r\u00e9f\u00e9rer \u00e0 [&hellip;]<\/p>\n","protected":false},"author":73172,"featured_media":0,"parent":96214,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mhh_sticky_footer_settings":{"entityId":0},"_mhh_sticky_footer_posts":"","_mhh_sticky_footer_expanded":false,"_mhh_mcn_text_direction":"","_mhh_mcn_language":"","_mhh_mcn_left_sidebar_settings":{"entityId":0},"_mhh_mcn_sidebar_settings":{"entityId":0},"mhh_mcn_side_navigation_style":{"fontSize":{"l":"","m":"","s":""},"lineHeight":{"l":1.5,"m":1.5,"s":1.5},"itemColor":"","hoverItemColor":"","currentItemColor":"","borderItemColor":"","backgroundItemHoverColor":"","themeColor":""},"_mhh_mcn_child_page_navigation":{"isActive":false,"isSticky":false},"hide_header":false,"show_top_bar":false,"hide_footer":false,"full_width_layout":false,"icon":null,"job_code":"","primary_tag":1608,"editor_notices":[],"mconnectHideShareThis":false,"footnotes":"","mconnectIsArchiveTemplate":false,"mconnectArchiveFiltersDisabled":false,"mconnectArchiveLockAllPresetFilters":false,"mconnectArchiveHidePageSubmenu":false,"mconnectArchiveShowParentPageOnly":false,"mconnectArchiveDefaultOrder":"DESC","mconnectArchiveDefaultOrderBy":"date","mconnectArchivePostsPerPage":12,"mconnectArchivePostTypes":[],"mconnectArchiveAllowFilterBy":["category","tx-content-type","tx-product","tx-pathology","tx-active-ingredient","tx-therapeutic-area"],"mconnectArchiveTaxonomyOrder":[],"mconnectArchiveFilterSorting":["active","is_keyword","is_date"],"mconnectArchiveContentItemStyle":{"showExcerpt":true,"showImage":true,"showIcon":false,"showPrimaryTag":true,"showBorder":false,"showDates":false,"showCta":true,"isCard":false,"hasBackground":false,"showMetadata":true},"mconnectArchiveLayout":{"type":"list","hasFeatured":false},"mconnectDynamicTaxonomyEntities":[],"mconnectArchiveTerms_category":[],"mconnectArchiveAllowTerms_category":[],"mconnectArchiveTerms_tx-content-type":[],"mconnectArchiveAllowTerms_tx-content-type":[],"mconnectArchiveTerms_tx-product":[],"mconnectArchiveAllowTerms_tx-product":[],"mconnectArchiveTerms_tx-pathology":[],"mconnectArchiveAllowTerms_tx-pathology":[],"mconnectArchiveTerms_tx-active-ingredient":[],"mconnectArchiveAllowTerms_tx-active-ingredient":[],"mconnectArchiveTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_dynamic-taxonomy":[],"mconnectArchiveLegacyDefaultTermsApplied":false,"mconnectContentUpdatesPerPage":10,"mconnectContentUpdatesViewMoreUrl":"","mconnectContentUpdatesTerms_tx-content-type":[],"mconnectContentUpdatesTerms_tx-product":[],"mconnectContentUpdatesTerms_tx-pathology":[],"mconnectContentUpdatesTerms_tx-active-ingredient":[],"mconnectContentUpdatesTerms_tx-therapeutic-area":[],"sidebar_toogle":0,"sidebar_toogle_notification_warning":true,"sidebar_toogle_notification_alert":true,"content_expiration_sidebar_date":"","content_expiration_sidebar_expired_post_status":"","content_expiration_sidebar_redirection":""},"categories":[1607],"tags":[1608],"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[957],"ga4_page_businessunit":[962],"ga4_page_campaign":[],"ga4_page_content_purpose":[1535],"ga4_page_customer_journey_stage":[],"ga4_page_customer_specialty":[],"ga4_page_experience":[],"ga4_page_indication":[],"ga4_page_material_intent":[1206],"ga4_page_product":[1336],"ga4_page_region":[1462],"ga4_page_therapeuticarea":[1513],"tx-therapeutic-area":[789],"tx-product":[1745],"tx-pathology":[],"tx-content-type":[1609],"tx-active-ingredient":[],"access":[],"user_status":[],"user_role":[],"class_list":["post-97799","page","type-page","status-publish","hentry","category-kfi","tag-kfi"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Information professionnelle abr\u00e9g\u00e9e de Lyfnua\u00ae (gefapixant) - MyMSD.ch FR<\/title>\n<meta name=\"robots\" content=\"noindex, nofollow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Information professionnelle abr\u00e9g\u00e9e de Lyfnua\u00ae (gefapixant) - MyMSD.ch FR\" \/>\n<meta property=\"og:description\" content=\"Information professionnelle abr\u00e9g\u00e9e de Lyfnua\u00ae (gefapixant) \u25bc Ce m\u00e9dicament fait l\u2019objet d\u2019une surveillance suppl\u00e9mentaire. 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