{"id":34429,"date":"2021-11-16T13:14:37","date_gmt":"2021-11-16T13:14:37","guid":{"rendered":"https:\/\/www.mymsd.ch\/de\/?page_id=34429"},"modified":"2025-11-23T17:01:47","modified_gmt":"2025-11-23T17:01:47","slug":"chronischer-husten","status":"publish","type":"page","link":"https:\/\/www.mymsd.ch\/de\/chronischer-husten\/","title":{"rendered":"Chronischen Husten"},"content":{"rendered":"\n
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Chronischer Husten<\/mark> bei Erwachsenen wird
\u00fcber die Dauer definiert[1]<\/sup><\/h1>\n\n\n\n
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\"Timeline<\/figure>\n\n\n\n
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Wenn Ihr Patient jedoch trotz angemessener Behandlung und klinischer Untersuchung immer noch chronischen Husten hat, sollte refrakt\u00e4rer chronischer Husten (RCC) oder unerkl\u00e4rlicher chronischer Husten (UCC) als Diagnose in Betracht gezogen werden.[2-4]<\/sup><\/p>\n\n\n\n

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Diagnostik<\/mark><\/h2>\n\n\n\n

In der Diagnostik des chronischen Hustens hat sich ein
abgestuftes Vorgehen bew\u00e4hrt. Die Basisdiagnostik stellt dabei den ersten Schritt dar, diese ist bei jedem Patienten mit einem chronischen Husten unabdingbar. Die Basisdiagnostik umfasst eine ausfu\u0308hrliche Anamnese, eine klinische und lungenfunktionelle Untersuchung sowie ein R\u00f6ntgen-Thorax.[1,5]<\/sup><\/p>\n\n\n

\n \n Erfahren Sie mehr<\/span>\n <\/a><\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n <\/div>\n<\/section>\n\n\n\n
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Pathomechanismus<\/mark><\/h2>\n\n\n\n

Im Gegensatz zu einem sch\u00fctzenden Hustenreflex, der eine Reaktion auf mechanische Reize wie eingeatmete Partikel oder aspirierten Mageninhalt ist; oder durch Absinken des pH-Wertes ausgel\u00f6st werden kann,[6,8-10]<\/sup> entstehen RCC\/UCC durch Entz\u00fcndungsmediatoren, Signalmolek\u00fcle oder chemische Reizstoffe.[6,7,9,11]<\/sup><\/p>\n\n\n

\n \n Erfahren Sie mehr<\/span>\n <\/a><\/div>\n\n<\/div>\n\n\n
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\"lung<\/figure>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n\n
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Patienten und Lebensqualit\u00e4t<\/mark><\/h2>\n\n\n\n

Patienten mit refrakt\u00e4rem chronischen Husten oder unerkl\u00e4rlichem chronischen Husten gehen einen schwierigen Weg bis zur Diagnose. Sie haben m\u00f6glicherweise das Gefu\u0308hl, dass ihr Zustand nicht richtig behandelt wird, da sie fortlaufend von einem Arzt zum anderen u\u0308berwiesen werden, w\u00e4hrend sie gleichzeitig unter chronischem Husten leiden, der ihre Lebensqualit\u00e4t beeintr\u00e4chtigt.[4,12,13]<\/sup><\/p>\n\n\n

\n \n Erfahren Sie mehr<\/span>\n <\/a><\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n\n

Quiz: Wie viel wissen Sie \u00fcber <\/mark>
chronischen Husten?<\/mark><\/h2>\n\n\n
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Husten ist ein grundlegender Schutzreflex gegen\u00fcber Reizungen der Atemwege. Dauert der Husten l\u00e4nger als 8 Wochen, spricht man von chronischem Husten, welcher die gesundheitsbezogene Lebensqualit\u00e4t des Patienten beeintr\u00e4chtigen kann.[1,12]<\/sup><\/strong><\/p>\n\n\n\n

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Abonnieren um Neuigkeiten \u00fcber chronischen Husten zu erhalten<\/a><\/div>\n<\/div>\n\n <\/div>\n<\/section>\n\n\n
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Patienten Profil<\/strong><\/h4>\n\n\n\n

Ein Patient mit chronischem Husten stellt sich typischerweise mit einem anhaltenden Husten von mehr als 8 Wochen vor.[1,12]<\/sup><\/p>\n\n\n

\n \n Erfahren Sie mehr ><\/span>\n <\/a><\/div>\n\n<\/div>\n\n\n
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Pathomechanismus<\/strong><\/h4>\n\n\n\n

Im Gegensatz zu einem sch\u00fctzenden Hustenreflex, der eine Reaktion auf mechanische Reize wie eingeatmete Partikel oder aspirierten Mageninhalt ist; oder durch Absinken des pH-Wertes ausgel\u00f6st werden kann,[6,8-10]<\/sup> entstehen RCC\/UCC durch Entz\u00fcndungsmediatoren, Signalmolek\u00fcle oder chemische Reizstoffe.[6,7,9,11]<\/sup><\/p>\n\n\n

\n \n Erfahren Sie mehr ><\/span>\n <\/a><\/div>\n\n<\/div>\n\n\n
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Diagnostik<\/strong><\/h4>\n\n\n\n

Um refrakt\u00e4ren chronischen Husten \/ unerkl\u00e4rlichen chronischen Husten zu diagnostizieren und den Patienten zu helfen, ihren Zustand besser zu verstehen, hat sich ein abgestuftes Vorgehen bew\u00e4hrt.[1,5]<\/sup><\/p>\n\n\n

\n \n Erfahren Sie mehr ><\/span>\n <\/a><\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n\n\n
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Referenzen:<\/mark><\/strong><\/h5>\n\n\n\n
    \n \n
  1. \n Morice AH, Millqvist E, Bieksiene K, et al. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J 2020;55(1):1901136. <\/li>\n\n\n
  2. \n Irwin RS, French CL, Chang AB, Altman KW; CHEST Expert Cough Panel. Classification of cough as a symptom in adults and management algorithms: CHEST Guideline and Expert Panel Report. Chest 2018;153(1):196-209. <\/li>\n\n\n
  3. \n Gibson P, Wang G, McGarvey L, et al. Treatment of unexplained chronic cough: CHEST Guideline and Expert Panel Report. Chest 2016;149(1):27-44. <\/li>\n\n\n
  4. \n Mazzone SB, McGarvey L. Mechanisms and Rationale for Targeted Therapies in Refractory and Unexplained Chronic Cough. Clin Pharmacol Therapeut 2020. Epub ahead of print. Doi: 10.1002\/cpt.2003. <\/li>\n\n\n
  5. \n AWMF (Deutsche Gesellschaft fu\u0308r Pneumologie und Beatmungsmedizin e.V. [DGP], Deutsche Gesellschaft fu\u0308r Allgemein- und Viszeralchirurgie e.V. [DGAV]). S2k-Leitlinie der Deutschen Gesellschaft fu\u0308r Pneumologie und Beatmungsmedizin zur Diagnostik und Therapie von erwachsenen Patienten mit Husten. Stand 01.01.2019. AWMF-RegisterNr.: 020-003.<\/mark> <\/li>\n\n\n
  6. \n Mazzone SB, Undem BJ. Vagal Afferent innervation of the airways in health and disease. Physiol Rev 2016;96:975-1024. <\/li>\n\n\n
  7. \n Canning BJ, Chang AB, Bolser DC, et al on behalf of the CHEST Expert Cough Panel. Anatomy and Neurophysiology of Cough. CHEST Guideline and Expert Panel Report. CHEST 2014;146(6):1633-1648. <\/li>\n\n\n
  8. \n West PW, Canning BJ, Merlo-Pich E, Woodcock AA, Smith JA. Morphologic Characterization of Nerves in Whole-Mount Airway Biopsies. Am J Resp Crit Care Med 2015;192(1):30-39. <\/li>\n\n\n
  9. \n Sun H, Kollarik M, Undem BJ. Blocking voltage-gated sodium channels as a strategy to suppress pathological cough. Pulm Pharmacol Ther 2017;47:38-41. <\/li>\n\n\n
  10. \n Canning BJ. Functional implications of the multiple afferent pathways regulating cough. Pulm Pharmacol Ther 2011;24:295-299. <\/li>\n\n\n
  11. \n Mazzone SB, Chung KF, McGarvey L. The heterogeneity of chronic cough: a case for the endotypes of cough hypersensitivity. Lancet Respir Med 2018;6(8):636-646. <\/li>\n\n\n
  12. \n Satia I, Badri H, Al-Sheklly B, Smith JA, Woodcock AA. Towards understanding and managing chronic cough. Clin Med (Lond) 2016;16(Suppl 6):s92-s97.<\/mark> <\/li>\n\n\n
  13. \n Chamberlain SA, Garrod R, Douiri A, et al. The impact of chronic cough: a cross-sectional European survey. Lung 2015;193(3):401-408.<\/mark> <\/li>\n\n<\/ol>\n\n\n\n

    Kopien der hier erw\u00e4hnten Publikation k\u00f6nnen bei Bedarf unter dpoc.switzerland@msd.com<\/a> angefragt werden.<\/mark><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

    Chronischer Husten bei Erwachsenen wird \u00fcber die Dauer definiert[1] Wenn Ihr Patient jedoch trotz angemessener Behandlung und klinischer Untersuchung immer 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