{"id":120480,"date":"2025-08-22T06:16:58","date_gmt":"2025-08-22T06:16:58","guid":{"rendered":"https:\/\/www.mymsd.ch\/de\/?page_id=120480"},"modified":"2026-02-17T09:12:28","modified_gmt":"2026-02-17T09:12:28","slug":"welireg","status":"publish","type":"page","link":"https:\/\/www.mymsd.ch\/de\/succinctstatement\/welireg\/","title":{"rendered":"KFI WELIREG\u00ae"},"content":{"rendered":"<figure class=\"mhh-mcn-v1-image mhh-mcn-v1-image--align-full mhh-mcn-v1-image--10ed6ebbf74a0df3335d1f89a46fd259 mhh-mcn-v1-image--align-items-center\">\n                    <img loading=\"lazy\" decoding=\"async\"\n        class=\"mhh-mcn-image mhh-mcn-image--full wp-image-123597\"\n        src=\"https:\/\/www.mymsd.ch\/de\/wp-content\/uploads\/sites\/13\/2025\/08\/D-WELIREG-Banner-SPI-202508.jpg?quality=80&#038;lossy=1\"\n        width=\"1024\"\n        height=\"256\"\n                alt=\"WELIREG KFI Banner\"\n            \/>\n            <\/figure>\n\n\n\n<h1 class=\"wp-block-heading  has-border-color has-has-red-border-color-border-color mhh-mcn-v1-heading--left mhh-mcn-v1-heading mhh-mcn-v1-heading--f6d8b9592a64a74dc3739ecea2fb656e\"><mark style=\"color:#123a8a\" class=\"has-inline-color\">Kurzfachinformation WELIREG\u00ae (Belzutifan)<\/mark><\/h1>\n\n\n\n<p class=\"has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--9d7c26b88810f4515a5cf1faca77ee29\"><em>\u25bc Dieses Arzneimittel unterliegt einer zus\u00e4tzlichen \u00dcberwachung. F\u00fcr weitere Informationen, siehe die Fachinformation WELIREG<strong><sup>\u00ae<\/sup><\/strong> auf <a href=\"https:\/\/www.swissmedicinfo-pro.ch\/ShowText.aspx?textType=FI&amp;lang=DE&amp;authNr=68531&amp;supportMultipleResults=1\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">www.swissmedicinfo-pro.ch<\/a>.<\/em><br><br><strong>WELIREG\u00ae<\/strong>: <strong>W<\/strong>: Belzutifan; <strong>I<\/strong>: Als Monotherapie zur Behandlung erwachsener Patienten mit nicht resezierbarem fortgeschrittenem klarzelligem Nierenzellkarzinom (RCC), das nach zwei oder mehr Therapielinien, darunter einen PD-(L)1-Inhibitor und einen VEGF-Tyrosinkinase-Inhibitor, progredient war; <strong>D<\/strong>: 120 mg (drei Tabletten \u00e0 40 mg), oral, einmal t\u00e4glich, bis zur Krankheitsprogression oder bis zum Auftreten einer nicht akzeptablen Toxizit\u00e4t; bei unerw\u00fcnschten Wirkungen Dosis anpassen; bei schwerer Nierenfunktionsst\u00f6rung Dosis anpassen. <strong>Weitere Indikationen und die dazugeh\u00f6rigen Dosierungen f\u00fcr Erwachsene entnehmen Sie bitte der Fachinformation<\/strong>. <strong>KI<\/strong>: \u00dcberempfindlichkeit gegen\u00fcber Wirk-\/Hilfsstoffen; <strong>WH<\/strong>: An\u00e4mie aufgrund von vermindertem Erythropoetin: regelm\u00e4ssig \u00fcberwachen und bei An\u00e4mie Dosis anpassen. Hypoxie: kann schwere Hypoxie verursachen, Sauerstoffs\u00e4ttigung \u00fcberwachen, Rauchstopp empfohlen, Dosis reduzieren oder absetzen. Embryofetale Toxizit\u00e4t: Kann den Fetus sch\u00e4digen oder zum Verlust des Fetus f\u00fchren, hochwirksam nichthormonell verh\u00fcten. Kann die Fertilit\u00e4t beintr\u00e4chtigen; <strong>DDI<\/strong>: Gleichzeitige Gabe mit CYP3A4-Substraten (inkl. hormonelle Verh\u00fctungsmittel), kann deren Wirksamkeit herabsetzen. Gleichzeitige Gabe mit UGT2B17- oder CYP2C19-Inhibitoren steigert die Plasmaexposition von Belzutifan, was unerw\u00fcnschte Wirkungen erh\u00f6hen kann; <strong>S\/S<\/strong>: Nicht empfohlen; vor Belzutifan Behandlung Schwangerschaftstest bei geb\u00e4rf\u00e4higen Frauen; hochwirksame nichthormonelle Empf\u00e4ngnisverh\u00fctung bei Frauen im geb\u00e4rf\u00e4higen Alter und bei M\u00e4nnern mit Partnerinnen im geb\u00e4rf\u00e4higen Alter; <strong>UAW (sehr h\u00e4ufig)<\/strong>: An\u00e4mie, M\u00fcdigkeit\/Ersch\u00f6pfung, Schmerzen des Muskel- und Skelettsystems, \u00dcbelkeit, Obstipation, Dyspnoe, Kopfschmerzen, Schwindel, Hypoxie, Alaninaminotransferase erh\u00f6ht, Aspartataminotransferase erh\u00f6ht; <strong>P<\/strong>: 90 Filmtabletten \u00e0 40 mg; <strong>AK<\/strong>: A; <strong>Z<\/strong>: MSD Merck Sharp &amp; Dohme AG, Werftestrasse 4, 6005 Luzern, Schweiz; (V2.0); CH-BEL-00013.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-gray-300-color has-alpha-channel-opacity has-gray-300-background-color has-background\" \/>\n\n\n\n<p class=\"has-border-color has-has-red-border-color-border-color has-black-color has-text-color has-link-color has-object-object-font-size wp-elements-36000db9ef0875daf361110595bac74f   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--0adab6885796b1fe0b0c099b8e550836\"><em>Konsultieren Sie bitte vor einer Verschreibung die vollst\u00e4ndige Fachinformation publiziert auf\u00a0<a href=\"https:\/\/www.swissmedicinfo-pro.ch\/ShowText.aspx?textType=FI&amp;lang=DE&amp;authNr=68531\" target=\"_blank\" rel=\"noreferrer noopener\">www.swissmedicinfo-pro.ch<\/a>.<\/em><\/p>\n\n\n<div class=\"mhh-mcn-v1-links mhh-mcn-v1-links--ffc3b2b6c7a69dd3cfce23a52c1b948d\">\n    <a class=\"mhh-mcn-v1-link mhh-mcn-v1-link--e410879471ce28501f3f5d0d3e4f05fc mhh-mcn-v1-link--is-variation mhh-mcn-v1-link--button-custom\" href=\"https:\/\/www.swissmedicinfo-pro.ch\/showText.aspx?textType=FI&#038;lang=DE&#038;authNr=68531&#038;supportMultipleResults=1\" target=\"_blank\" rel=\"noopener noreferrer\" aria-label=\"Fachinformation WELIREG\u00ae\">\n                    <span class=\"mhh-mcn-v1-link__label\">Fachinformation WELIREG\u00ae<\/span>\n                <\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Kurzfachinformation WELIREG\u00ae (Belzutifan) \u25bc Dieses Arzneimittel unterliegt einer zus\u00e4tzlichen \u00dcberwachung. F\u00fcr weitere Informationen, siehe die Fachinformation WELIREG\u00ae auf www.swissmedicinfo-pro.ch. WELIREG\u00ae: [&hellip;]<\/p>\n","protected":false},"author":202221,"featured_media":123595,"parent":114174,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mhh_sticky_footer_settings":{"entityId":0},"_mhh_sticky_footer_posts":"","_mhh_sticky_footer_expanded":false,"_mhh_mcn_text_direction":"","_mhh_mcn_language":"","_mhh_mcn_left_sidebar_settings":{"entityId":0},"_mhh_mcn_sidebar_settings":{"entityId":0},"mhh_mcn_side_navigation_style":{"fontSize":{"l":"","m":"","s":""},"lineHeight":{"l":1.5,"m":1.5,"s":1.5},"itemColor":"","hoverItemColor":"","currentItemColor":"","borderItemColor":"","backgroundItemHoverColor":"","themeColor":""},"_mhh_mcn_child_page_navigation":{"isActive":false,"isSticky":false},"hide_header":false,"show_top_bar":false,"hide_footer":false,"full_width_layout":false,"icon":null,"job_code":"","primary_tag":1711,"editor_notices":[],"mconnectHideShareThis":false,"footnotes":"","mconnectIsArchiveTemplate":false,"mconnectArchiveFiltersDisabled":false,"mconnectArchiveLockAllPresetFilters":false,"mconnectArchiveHidePageSubmenu":false,"mconnectArchiveShowParentPageOnly":false,"mconnectArchiveDefaultOrder":"DESC","mconnectArchiveDefaultOrderBy":"date","mconnectArchivePostsPerPage":12,"mconnectArchivePostTypes":[],"mconnectArchiveAllowFilterBy":["category","tx-content-type","tx-product","tx-pathology","tx-active-ingredient","tx-therapeutic-area"],"mconnectArchiveTaxonomyOrder":[],"mconnectArchiveFilterSorting":["active","is_keyword","is_date"],"mconnectArchiveContentItemStyle":{"showExcerpt":true,"showImage":true,"showIcon":false,"showPrimaryTag":true,"showBorder":false,"showDates":false,"showCta":true,"isCard":false,"hasBackground":false,"showMetadata":true},"mconnectArchiveLayout":{"type":"list","hasFeatured":false},"mconnectDynamicTaxonomyEntities":[],"mconnectArchiveTerms_category":[],"mconnectArchiveAllowTerms_category":[],"mconnectArchiveTerms_tx-content-type":[],"mconnectArchiveAllowTerms_tx-content-type":[],"mconnectArchiveTerms_tx-product":[],"mconnectArchiveAllowTerms_tx-product":[],"mconnectArchiveTerms_tx-pathology":[],"mconnectArchiveAllowTerms_tx-pathology":[],"mconnectArchiveTerms_tx-active-ingredient":[],"mconnectArchiveAllowTerms_tx-active-ingredient":[],"mconnectArchiveTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_dynamic-taxonomy":[],"mconnectArchiveLegacyDefaultTermsApplied":false,"mconnectContentUpdatesPerPage":10,"mconnectContentUpdatesViewMoreUrl":"","mconnectContentUpdatesTerms_tx-content-type":[],"mconnectContentUpdatesTerms_tx-product":[],"mconnectContentUpdatesTerms_tx-pathology":[],"mconnectContentUpdatesTerms_tx-active-ingredient":[],"mconnectContentUpdatesTerms_tx-therapeutic-area":[],"sidebar_toogle":0,"sidebar_toogle_notification_warning":true,"sidebar_toogle_notification_alert":true,"content_expiration_sidebar_date":"","content_expiration_sidebar_expired_post_status":"","content_expiration_sidebar_redirection":""},"categories":[],"tags":[1711],"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[989],"ga4_page_businessunit":[995],"ga4_page_campaign":[],"ga4_page_content_purpose":[1636],"ga4_page_customer_journey_stage":[],"ga4_page_customer_specialty":[],"ga4_page_experience":[],"ga4_page_indication":[],"ga4_page_material_intent":[1208],"ga4_page_product":[1224],"ga4_page_region":[1563],"ga4_page_therapeuticarea":[1593],"tx-therapeutic-area":[776,627],"tx-product":[970],"tx-pathology":[],"tx-content-type":[1712],"tx-active-ingredient":[],"access":[],"user_status":[],"user_role":[],"class_list":["post-120480","page","type-page","status-publish","has-post-thumbnail","hentry","tag-kfi"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>KFI WELIREG\u00ae - MyMSD.ch DE<\/title>\n<meta name=\"robots\" content=\"noindex, nofollow\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"KFI WELIREG\u00ae - MyMSD.ch DE\" \/>\n<meta property=\"og:description\" content=\"Kurzfachinformation WELIREG\u00ae (Belzutifan) \u25bc Dieses Arzneimittel unterliegt einer zus\u00e4tzlichen \u00dcberwachung. 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