{"id":116676,"date":"2024-10-11T15:30:22","date_gmt":"2024-10-11T15:30:22","guid":{"rendered":"https:\/\/www.mymsd.ch\/de\/?page_id=116676"},"modified":"2026-02-19T17:36:07","modified_gmt":"2026-02-19T17:36:07","slug":"winrevair","status":"publish","type":"page","link":"https:\/\/www.mymsd.ch\/de\/succinctstatement\/winrevair\/","title":{"rendered":"KFI WINREVAIR\u00ae (Sotatercept)"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-border-color has-has-red-border-color-border-color  mhh-mcn-v1-heading mhh-mcn-v1-heading--096f310846bd379ce3bc622f724a3d6f\"><mark class=\"has-inline-color has-teal-500-color\">Kurzfachinformation WINREVAIR<sup>\u00ae<\/sup> (Sotatercept)<\/mark><\/h1>\n\n\n\n<p class=\"has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--ccff96f5caef33493e633691daf02bf7\">\u25bc Dieses Arzneimittel unterliegt einer zus\u00e4tzlichen \u00dcberwachung. F\u00fcr weitere Informationen, siehe Fachinformation (WINREVAIR\u00ae) auf <a href=\"https:\/\/www.swissmedicinfo-pro.ch\/ShowText.aspx?textType=FI&amp;lang=DE&amp;authNr=69787\" target=\"_blank\" rel=\"noreferrer noopener\">www.swissmedicinfo-pro.ch<\/a>.<\/p>\n\n\n\n<p class=\"has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--ae57f6c1eca510cf4ec29375bd533f2a\"><strong>WINREVAIR\u00ae:<\/strong> <strong>W:<\/strong> Sotatercept; <strong>I:<\/strong> In Kombination mit einer Standardtherapie f\u00fcr die pulmonale arterielle Hypertonie (PAH), zur Langzeit-Behandlung von PAH bei erwachsenen Patienten mit WHO-Funktionsklasse II, III und IV; <strong>D:<\/strong> Erwachsene: einmal alle 3 Wochen als subkutane Injektion in Abh\u00e4ngigkeit vom K\u00f6rpergewicht; vor der ersten Dosis H\u00e4moglobin-(Hb-)Wert und Thrombozytenzahl bestimmen; Anfangsdosis: 0,3 mg\/kg; vor Erh\u00f6hung auf Zieldosis Hb-Wert und Thrombozytenzahl \u00fcberpr\u00fcfen; Zieldosis: 0,7 mg\/kg alle 3 Wochen; Dosierungsanpassungen aufgrund eines H\u00e4moglobin-Anstiegs oder einer Verminderung der Thrombozytenzahl: Hb-Wert und Thrombozytenzahl mind. vor jeder Dosis f\u00fcr die ersten 5 Dosen kontrollieren; Anwendung: Nach Rekonstitution als subkutane Injektion im Bereich Bauch (mind. 5 cm vom Nabel entfernt), Oberarm oder Oberschenkel verabreichen; <strong>KI:<\/strong> \u00dcberempfindlichkeit gegen\u00fcber Wirk-\/Hilfsstoffen; <strong>WH:<\/strong> Erythrozytose; schwere Thrombozytopenie; schwerwiegende Blutungen; Embryofetale Toxizit\u00e4t; beeintr\u00e4chtigte Fertilit\u00e4t; Einschr\u00e4nkung der klinischen Daten: Keine PAH-Patienten mit HIV, portaler Hypertonie, Bilharziose oder PVOD eingeschlossen; <strong>DDI:<\/strong> Keine Interaktionsstudien durchgef\u00fchrt; <strong>S\/S:<\/strong> Schwangerschaft: Nicht empfohlen, Empf\u00e4ngnisverh\u00fctung; Stillen: Nicht empfohlen; <strong>UAW (sehr h\u00e4ufig):<\/strong> Thrombozytopenie, erh\u00f6htes H\u00e4moglobin, Schwindel, Kopfschmerzen, Epistaxis, Diarrhoe, Zahnfleischbluten, Teleangiektasie, Ausschlag; <strong>P:<\/strong> Set mit 45 mg bzw. 60 mg Pulver\/Durchstechflasche und L\u00f6sungsmittel zur Herstellung einer Injektionsl\u00f6sung in jeweils zwei Packungen erh\u00e4ltlich: Packung mit 1 (bzw. 2) Durchstechflasche mit Pulver, 1 (bzw. 2) vorgef\u00fcllte Spritze mit L\u00f6sungsmittel, 1 Dosierspritze, 1 (bzw. 2) Durchstechflaschen-Adapter, 1 Injektionsnadel und 4 (bzw. 8) Alkoholtupfer; <strong>AK:<\/strong> B; <strong>Z:<\/strong> MSD Merck Sharp &amp; Dohme AG, B\u00fcrgenstrasse 8, 6005 Luzern, Schweiz; (V2.1); CH-SOT-00052.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-gray-300-color has-alpha-channel-opacity has-gray-300-background-color has-background\" \/>\n\n\n\n<p class=\"has-gray-800-color has-text-color has-object-object-font-size has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--abcc8033337e3a89443e4f758c5ba290\"><em>Konsultieren Sie bitte vor einer Verschreibung die vollst\u00e4ndige Fachinformation, publiziert auf der Homepage von Swissmedic (<a href=\"https:\/\/www.swissmedicinfo-pro.ch\/ShowText.aspx?textType=FI&amp;lang=DE&amp;authNr=69787\" target=\"_blank\" rel=\"noreferrer noopener\">www.swissmedicinfo-pro.ch)<\/a>.<\/em><\/p>\n\n\n\n<p dir=\"ltr\" lang=\"en-US\" class=\"has-border-color has-has-red-border-color-border-color   mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--f279dcf193b60e355df99dd9cbefba61\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Kurzfachinformation WINREVAIR\u00ae (Sotatercept) \u25bc Dieses Arzneimittel unterliegt einer zus\u00e4tzlichen \u00dcberwachung. F\u00fcr weitere Informationen, siehe Fachinformation (WINREVAIR\u00ae) auf www.swissmedicinfo-pro.ch. WINREVAIR\u00ae: W: [&hellip;]<\/p>\n","protected":false},"author":73172,"featured_media":0,"parent":114174,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mhh_sticky_footer_settings":{"entityId":0},"_mhh_sticky_footer_posts":"","_mhh_sticky_footer_expanded":false,"_mhh_mcn_text_direction":"ltr","_mhh_mcn_language":"en_US","_mhh_mcn_left_sidebar_settings":{"entityId":0},"_mhh_mcn_sidebar_settings":{"entityId":0},"mhh_mcn_side_navigation_style":{"fontSize":{"l":"","m":"","s":""},"lineHeight":{"l":1.5,"m":1.5,"s":1.5},"itemColor":"","hoverItemColor":"","currentItemColor":"","borderItemColor":"","backgroundItemHoverColor":"","themeColor":""},"_mhh_mcn_child_page_navigation":{"isActive":false,"isSticky":false},"hide_header":false,"show_top_bar":false,"hide_footer":false,"full_width_layout":false,"icon":null,"job_code":"","primary_tag":1711,"editor_notices":[],"mconnectHideShareThis":false,"footnotes":"","mconnectIsArchiveTemplate":false,"mconnectArchiveFiltersDisabled":false,"mconnectArchiveLockAllPresetFilters":false,"mconnectArchiveHidePageSubmenu":false,"mconnectArchiveShowParentPageOnly":false,"mconnectArchiveDefaultOrder":"DESC","mconnectArchiveDefaultOrderBy":"date","mconnectArchivePostsPerPage":12,"mconnectArchivePostTypes":[],"mconnectArchiveAllowFilterBy":["category","tx-content-type","tx-product","tx-pathology","tx-active-ingredient","tx-therapeutic-area"],"mconnectArchiveTaxonomyOrder":[],"mconnectArchiveFilterSorting":["active","is_keyword","is_date"],"mconnectArchiveContentItemStyle":{"showExcerpt":true,"showImage":true,"showIcon":false,"showPrimaryTag":true,"showBorder":false,"showDates":false,"showCta":true,"isCard":false,"hasBackground":false,"showMetadata":true},"mconnectArchiveLayout":{"type":"list","hasFeatured":false},"mconnectDynamicTaxonomyEntities":[],"mconnectArchiveTerms_category":[],"mconnectArchiveAllowTerms_category":[],"mconnectArchiveTerms_tx-content-type":[],"mconnectArchiveAllowTerms_tx-content-type":[],"mconnectArchiveTerms_tx-product":[],"mconnectArchiveAllowTerms_tx-product":[],"mconnectArchiveTerms_tx-pathology":[],"mconnectArchiveAllowTerms_tx-pathology":[],"mconnectArchiveTerms_tx-active-ingredient":[],"mconnectArchiveAllowTerms_tx-active-ingredient":[],"mconnectArchiveTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_dynamic-taxonomy":[],"mconnectArchiveLegacyDefaultTermsApplied":false,"mconnectContentUpdatesPerPage":10,"mconnectContentUpdatesViewMoreUrl":"","mconnectContentUpdatesTerms_tx-content-type":[],"mconnectContentUpdatesTerms_tx-product":[],"mconnectContentUpdatesTerms_tx-pathology":[],"mconnectContentUpdatesTerms_tx-active-ingredient":[],"mconnectContentUpdatesTerms_tx-therapeutic-area":[],"sidebar_toogle":0,"sidebar_toogle_notification_warning":true,"sidebar_toogle_notification_alert":true,"content_expiration_sidebar_date":"","content_expiration_sidebar_expired_post_status":"","content_expiration_sidebar_redirection":""},"categories":[1710],"tags":[1711],"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[989],"ga4_page_businessunit":[994],"ga4_page_campaign":[],"ga4_page_content_purpose":[1636],"ga4_page_customer_journey_stage":[],"ga4_page_customer_specialty":[],"ga4_page_experience":[],"ga4_page_indication":[],"ga4_page_material_intent":[1208],"ga4_page_product":[1896],"ga4_page_region":[1563],"ga4_page_therapeuticarea":[1608],"tx-therapeutic-area":[782],"tx-product":[1678],"tx-pathology":[],"tx-content-type":[1712],"tx-active-ingredient":[],"access":[],"user_status":[],"user_role":[],"class_list":["post-116676","page","type-page","status-publish","hentry","category-kfi","tag-kfi"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>KFI WINREVAIR\u00ae (Sotatercept) - MyMSD.ch DE<\/title>\n<meta name=\"robots\" content=\"noindex, nofollow\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"KFI WINREVAIR\u00ae (Sotatercept) - MyMSD.ch DE\" \/>\n<meta property=\"og:description\" content=\"Kurzfachinformation WINREVAIR\u00ae (Sotatercept) \u25bc Dieses Arzneimittel unterliegt einer zus\u00e4tzlichen \u00dcberwachung. 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